A Defence potion is made by mixing 1x Talupia blancus, 1x Orchicada blauand 1x Rosarius poppus in a potion stand requiring the player to have level 10 in the Herblore skill and making it awards the player 21 experience points in the skill.
Consuming this potion gives the player a 10% reduction in damage taken during combat for 15 minutes.